| Date | Location | Result | |
| Oct 16, 2010 | Reynoldsburg, Ohio | Columbus Fire 17, Detroit Seminoles 7 | Box score |
| Oct 9, 2010 | West High School | Columbus Fire 35, Southern Michigan 6 | Box score |
| Oct 09, 2010 | Trenton, Ohio | Detroit Seminoles 22, Kings Comets 20 | Box score |
| Oct 02, 2010 | Monroe, MI | Southern Michigan 22, Louisville Bulls 0 | Box score |
| Oct 02, 2010 | Detroit, Mich. | Detroit Seminoles 16, Indiana Mustangs 14 | Box score |
| Sep 26, 2010 | Noblesville, IN | Indiana Mustangs 39, Wisconsin Wolfpack 20 | Box score |
| Sep 25, 2010 | Monroe, MI | Columbus Fire 29, Southern Michigan 21 | Box score |
| Sep 25, 2010 | Louisville, KY | Kings Comets 17, Louisville Bulls 0 | Box score |
| Sep 18, 2010 | Birmingham, Mich. | Detroit Seminoles 28, Indiana Mustangs 0 | |
| Sep 18, 2010 | Flint, MI | Southern Michigan 14, Flint Fury 8 | Box score |
| Sep 18, 2010 | Columbus, OH | Columbus Fire 34, Louisville Bulls 13 | Box score |
| Sep 18, 2010 | Milwaukee, WI | Kings Comets 32, Wisconsin Wolfpack 0 | Box score |
| Sep 11, 2010 | Columbus, Ohio | Columbus Fire 34, Detroit Seminoles 29 | |
| Sep 11, 2010 | Newport, Ky | Kings Comets 34, Southern Michigan 12 | Box score |
| Sep 11, 2010 | Noblesville, In. | Indiana Mustangs 41, Flint Fury 0 | Box score |
| Aug 28, 2010 | Columbus, Ohio | Columbus Fire 29, Wisconsin Wolfpack 0 | |
| Aug 28, 2010 | Monroe, MI | Detroit Seminoles 28, Southern Michigan 21 | Box score |
| Aug 28, 2010 | Flint, MI | Louisville Bulls 23, Flint Fury 19 | Box score |
| Aug 21, 2010 | Birmingham, Mich. | Detroit Seminoles 40, Flint Fury 0 | |
| Aug 21, 2010 | Louisville, Ky | Louisville Bulls 13, Wisconsin Wolfpack 6 | Box score |
| Aug 21, 2010 | Noblesville, IN. | Columbus Fire 40, Indiana Mustangs 26 | Box score |
| Aug 14, 2010 | Monroe, MI | Southern Michigan 39, Indiana Mustangs 12 | Box score |
| Aug 14, 2010 | Kenosha, WI | Wisconsin Wolfpack 25, Flint Fury 22 | Box score |
| Aug 14, 2010 | Cincinnati, Ohio | Columbus Fire 26, Kings Comets 25 | Box score |
| Aug 07, 2010 | Louisville, KY | Louisville Bulls 44, Indiana Mustangs 6 | Box score |
| Aug 07, 2010 | Hart Park | Detroit Seminoles 43, Wisconsin Wolfpack 0 | Box score |
| Aug 07, 2010 | Flint, Mich. | Flint Fury 25, Kings Comets 21 | Box score |
| Jul 31, 2010 | Toledo, OH | Detroit Seminoles 40, Louisville Bulls 6 | Box score |
| Jul 31, 2010 | Toledo, Ohio | Kings Comets 48, Indiana Mustangs 0 | Box score |
| Jul 31, 2010 | Toledo | Southern Michigan 40, Wisconsin Wolfpack 14 | Box score |
| Jul 24, 2010 | New Albany, IN | Southern Michigan 26, Louisville Bulls 13 | Box score |
| Jul 24, 2010 | Columbus, Ohio | Columbus Fire 48, Flint Fury 0 | Box score |
| Jul 24, 2010 | Cincinnati, Ohio | Kings Comets 13, Detroit Seminoles 7 | Box score |